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A Broad Spectrum of Potential Etiologic Factors As with almost all disease states, a broad spectrum of both genetic and environmental factors have been suggested as contributing to the initiation and progression of PD

Significant findings were matched to KEGG (Kyoto Encyclopedia of Genes and Genomes) pathways to define metabolic modules and then integrated into a metabolomic map to compare to other studies

Moreover, as opposed to the use of methotrexate which is linked with an elevation in pro-oxidant levels, infliximab does not influence the pro-oxidant/antioxidant balance or can influence it in the favor of antioxidant molecules [86]

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